Volume: 54 Issue: 3
Year: 2023, Page: 29-35, Doi: https://doi.org/10.61649/kujos/v54i3.vernekar
Received: Sept. 21, 2022 Accepted: Jan. 2, 2023 Published: Nov. 9, 2023
In the present study, a green, cost-effective and robust approach for the synthesis of silver nanoparticles (AgNPs) using naturally available T. neotaliala fruits and freely available solar energy with no expenses on external conventional energy was employed. This approach favoured the formation of AgNPs within 5 mins of sunlight exposure with a colour change from colourless to reddish brown. The characterization done using analytical techniques such as UV-Vis spectroscopy, FTIR, XRD, DLS, Zeta Potential, AFM, HR-TEM and SAED revealed that the AgNPs had a characteristic absorption peak at 412 nm and were spherical, crystalline with FCC structure, sizes in between 10 to 50 nm and stable (-41.7 mV) which further confirmed their formation. As protein denaturation is one of the main causes of Inflammation, we further tested the effect of synthesized AgNPs on inhibition of BSA protein denaturation. Results depict maximum % inhibition of 73.68 % at its highest concentration i.e., 500 µg/mL in comparison with the diclofenac sodium, an anti-inflammatory drug (97.16 %) which revealed the potential of AgNPs to act as an anti-inflammatory agent.
Keywords: Green Synthesis, Photocatalyzed, HR-TEM, BSA Anti-denaturation, Terminalia mantaly H. Perrier
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