Volume: 54 Issue: 4
Year: 2023, Page: 84-90, Doi: https://doi.org/10.61649/kujos/v54i4.23.12
Received: Oct. 27, 2023 Accepted: Dec. 28, 2023 Published: Dec. 30, 2023
Cancer is a multifactorial group of diseases defined by the uncontrolled growth of cells. Prostate cancer is the second leading cancer in men and the fifth leading cause of death worldwide. However, the incidences of cancer have increased steadily over the years. Lifestyle changes and genetic factors are the leading causes of cancer. Seaweeds have been a source of food since ancient times, and studies have reported low incidences of cancers in countries consuming seaweed-rich diets. Marine macroalgae Ulva belonging to the family Ulvaceae have been reported to possess anticancer potential which is dominating the coastal regions of the world and across the coastal belt of India. Several studies have indicated that compounds extracted from seaweeds act as an effective anticancer agent. The biological benefit of seaweed potential in treating cancers was identified through epidemiological studies that showed a low incidence of the disease in both men and women consuming seaweed countries. By considering the potential of compounds present in the seaweeds to act against cancer cells, this review focuses on the multistep in vitro study protocol of deriving the crude seaweed extract and its identification. It also highlights the anticancer potential of seaweeds by MTT Assay and calls attention to the potential of compounds extracted from seaweed Ulva fasciata and Ulva lactuca and their effects against prostate cancer.
Keywords: Prostate Cancer; Ulva fasciata; Ulva lactuca; Epidemiology; Incidence; Extraction; Seaweed Compound
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