Volume: 54 Issue: 4
Year: 2023, Page: 73-78, Doi: https://doi.org/10.61649/kujos/v54i4.23.4
Received: Sept. 20, 2023 Accepted: Nov. 15, 2023 Published: Dec. 27, 2023
Simarouba glauca (SG) is known for exhibiting anti-inflammatory, anti-neoplastic, anti-diabetic and analgesic properties. The aim of this study is to analyze the phytochemical composition, presence of total phenols and flavonoids, anti-oxidant activity and Fourier Transform Infrared spectroscopy (FT-IR) and Gas Chromatography- Mass Spectroscopy (GC-MS) analysis of Simarouba glauca leaf extracts. The total phenolic content of chloroform and acetone extracts was 136.71 ± 0.06 and 98.35 ± 0.02 mg/g GAE respectively. The total flavonoid content of chloroform and acetone extracts was 311.06 ± 0.03 and 358 ± 0.05 mg/g QE respectively, which are higher than that of other extracts. Both acetone and methanol extracts showed higher anti-oxidant capacities in contrast to other solvent extracts. The Gas Chromatography- Mass Spectroscopy (GC-MS) analysis of methanol extract exhibited the presence of twenty-two major peaks. The biological activities of these compounds are discussed in the present study. The overall results of this work provide remarkable evidence for the use of the methanol fraction of Simarouba glauca as a competent source of phytochemicals that are effective against various diseases.
Keywords: GC-MS Analysis; FR-IR Analysis; Simarouba glauca; Anti-oxidant Activity
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