Karnatak University Journal of Science

Volume: 56 Issue: 1

  • Open Access
  • Original Article

An Inclusive Disquisition on Thiazoles as Possible Antifungal Agents

Namrata N Mundargi1, K Sujatha1,∗

1Department of Chemistry, Karnatak University, Dharwad, 580003, Karnataka, India


∗ Corresponding author email: [email protected]

Year: 2025, Page: 1-7, Doi: https://doi.org/10.61649/kujos/v56i1.24.sujatha

Received: Jan. 12, 2025 Accepted: Feb. 22, 2025 Published: March 10, 2025

Abstract

In recent years, antifungal medications have become increasingly ineffective due to antifungal resistance, which is one of the largest concerns facing the globe today. The inception of novel heterocycles that have substantial biological consequences has become vital owing to the advent of several epidemics and resistant bacteria. Numerous hybrid compounds are presently undergoing varying phases of clinical testing and could eventually be utilized in the therapeutic settings to address a range of ailments. In this overview, Nitrogen and sulfur-based heterocyclic aromatic compounds play a substantial and crucial role in medicine and the production of pharmacologically active substances. Thiazoles are highlighted for their crucial role, attributed to their wide array of biological activities within the field of medicinal chemistry. The emergence of antifungal resistance poses a considerable public health challenge as it diminishes the efficacy of antifungal treatments, leading to heightened rates of illness, mortality, and healthcare expenses. Given the foregoing, we have compiled an inventory of the most current developments in thiazoles as antifungal agents, encompassing papers reported from 2020 to 2024.

Keywords: Antifungal, Thiazoles

 

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Namrata N Mundargi, K Sujatha. An Inclusive Disquisition on Thiazoles as Possible Antifungal Agents. Karnatak University Journal of Science 56(1), (2025), 1–7
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